Fiche publication


Date publication

juillet 2016

Journal

Basic research in cardiology

Auteurs

Membres identifiés du Cancéropôle Est :
Dr PO Chrystelle


Tous les auteurs :
Vanhoutte L, Gerber BL, Gallez B, Po C, Magat J, Balligand JL, Feron O, Moniotte S

Résumé

Transgenic and gene knockout rodent models are primordial to study pathophysiological processes in cardiovascular research. Over time, cardiac MRI has become a gold standard for in vivo evaluation of such models. Technical advances have led to the development of magnets with increasingly high field strength, allowing specific investigation of cardiac anatomy, global and regional function, viability, perfusion or vascular parameters. The aim of this report is to provide a review of the various sequences and techniques available to image mice on 7-11.7 T magnets and relevant to the clinical setting in humans. Specific technical aspects due to the rise of the magnetic field are also discussed.

Mots clés

Cardiovascular diseases, High field, MRI, Mouse

Référence

Basic Res Cardiol. 2016 07;111(4):46