Fiche publication


Date publication

avril 2015

Journal

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation

Auteurs

Membres identifiés du Cancéropôle Est :
Pr MARIE Pierre-Yves , Pr GAUCHOTTE Guillaume


Tous les auteurs :
Liu Y, Maureira P, Gauchotte G, Falanga A, Marie V, Olivier A, Groubatch F, Gu C, Marie PY, Tran N

Résumé

Cardiac recovery is possible by means of mechanical unloading yet remains rare. Excessive unloading-associated myocardial atrophy and fibrosis may adversely affect the process of reverse remodeling. In this study, we sought to evaluate the effect of different intensities of chronic left ventricular (LV) unloading on myocardial remodeling.

Mots clés

Animals, Chronic Disease, Disease Models, Animal, Heart Transplantation, Male, Rats, Rats, Inbred Lew, Transplantation, Heterotopic, Ventricular Dysfunction, Left, physiopathology, Ventricular Remodeling

Référence

J. Heart Lung Transplant.. 2015 Apr;34(4):594-603