Matrix-assisted laser desorption ionization-time of flight mass spectrometry identifies Pseudomonas aeruginosa high-risk clones.

Date publication

avril 2015

Journal

Journal of clinical microbiology

Auteurs

Membres identifiés du Cancéropôle Est :
Pr HOCQUET Didier

Tous les auteurs :
Cabrolier N, Sauget M, Bertrand X, Hocquet D

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/25653397

Résumé

We show here that matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) accurately and quickly identified the five high-risk clones of Pseudomonas aeruginosa sequence type 111 (ST111), ST175, ST235, ST253, and ST395. The use of this screening technique by clinical microbiology laboratories may tackle the spread of high-risk clones by the quick implementation of hygiene control procedures for relevant patients.

Mots clés

Anti-Bacterial Agents, pharmacology, Bacterial Typing Techniques, Drug Resistance, Multiple, Bacterial, genetics, Phylogeny, Pseudomonas aeruginosa, drug effects, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

Référence

J. Clin. Microbiol.. 2015 Apr;53(4):1395-8