Fiche publication


Date publication

mars 2015

Journal

Seminars in cell & developmental biology

Auteurs

Membres identifiés du Cancéropôle Est :
Dr DUBREZ Laurence


Tous les auteurs :
Dubrez L, Rajalingam K

Résumé

Inhibitors of apoptosis (IAPs) constitute a family of cell signaling regulators controlling several fundamental biological processes such as innate immunity, inflammation, cell death, cell proliferation, and cell differentiation. Increasing evidence from in vivo and in vitro studies indicate a function for IAPs in the modulation of invasive and migratory properties of cells. Here, we present and discuss the mechanisms whereby IAPs can control cell migration.

Mots clés

Animals, Cell Adhesion, Cell Movement, Cytoskeleton, metabolism, Humans, Inhibitor of Apoptosis Proteins, metabolism, Signal Transduction

Référence

Semin. Cell Dev. Biol.. 2015 Mar;39:124-31