Fiche publication


Date publication

septembre 2022

Journal

Chemical communications (Cambridge, England)

Auteurs

Membres identifiés du Cancéropôle Est :
Dr BONNET Dominique


Tous les auteurs :
Maujean T, Marchand P, Wagner P, Riché S, Boisson F, Girard N, Bonnet D, Gulea M

Résumé

The HDA reaction of dithioesters was developed as a new click-reaction compatible with the indirect F-labelling of peptides. It involves dithioester-peptides and a radiofluorinated diene as a novel prosthetic group. The method was applied to a PSMA-ligand for the detection of LNCap tumors in xenografted mice.

Référence

Chem Commun (Camb). 2022 09 15;: