Fiche publication


Date publication

septembre 2022

Journal

Annales de cardiologie et d'angeiologie

Auteurs

Membres identifiés du Cancéropôle Est :
Pr COTTIN Yves , Pr VERGELY Catherine


Tous les auteurs :
Rochette L, Dogon G, Rigal E, Zeller M, Vergely C, Cottin Y

Résumé

In the recently published manuscript entitled "GDF15 a rising modulator of immunity and a strategy in Coronavirus disease 2019 (COVID-19) in relationship with iron metabolism" and we examined the potential properties of Growth and differentiation factor 15 (GDF15) as an emerging modulator of immunity in COVID-19. We commented new aspects of the biology of GDF15 and investigated the potential value of GDF15 as a biomarker. Is GDF15 a biomarker of the inflammatory process and oxidative stress state? Recently, it was reported that 1500 clinical trials related to COVID-19 have been registered, but none have yet found an optimal strategy. In these conditions, more clinical studies are needed before any of these agents can be considered antiviral agents.

Mots clés

Biomarker, COVID-19, Cardiovascular, GDF15, Immunity, biomarqueur, cardiovasculaire, immunité

Référence

Ann Cardiol Angeiol (Paris). 2022 09 16;: