Fiche publication


Date publication

février 2015

Journal

Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique

Auteurs

Membres identifiés du Cancéropôle Est :
Pr TAILLANDIER Luc


Tous les auteurs :
Le Rhun É, Taillibert S, Blonski M, Jouniaux Delbez N, Delgadillo D, Taillia H, Auquier P, Belin C, Bonnetain F, Varin D, Tallet A, Taillandier L

Résumé

Brain metastases impact on the survival of the patients, but on their quality of life as well. The objective of the management of these patients is then double. Currently, due to medical advances, survivals tend to improve, especially for some tumor subtypes. During the course of the disease, different neurological signs and symptoms can be observed according to the location, the number and the volume of the metastase(s). Patients and caregivers are especially worried about the loss of autonomy and cognitive impairments. A permanent dialogue, during the course of the disease, is mandatory, in order to adapt the management to the objectives determined by the patients and the medical team. These objectives may vary according to the objective response rates of the disease to anticancer therapies, according to the impact of the disease and its management in daily living. Anticancer therapies and supportive care must be appreciated according to their impact on the survival, on the preservation of the functional independence and the quality of life of the patient, on their abilities to preserve the neurological status and delay the apparition of new neurological signs and symptoms, and their adverse events. Supportive care, cognition and quality of life should be regularly evaluated and adapted according to the objectives of the management of brain metastases patients. Different approaches are described in this paper.

Mots clés

Activities of Daily Living, Adrenal Cortex Hormones, therapeutic use, Anticoagulants, therapeutic use, Anticonvulsants, therapeutic use, Automobile Driving, Brain Neoplasms, complications, Caregivers, psychology, Cognition Disorders, diagnosis, Combined Modality Therapy, Epilepsy, drug therapy, Humans, Intracranial Hypertension, drug therapy, Neurologic Examination, Neuropsychological Tests, Patient Education as Topic, Patients, psychology, Personal Autonomy, Quality of Life, Thromboembolism, etiology

Référence

Cancer Radiother. 2015 Feb;19(1):55-60