Fiche publication
Date publication
janvier 2015
Journal
PloS one
Auteurs
Membres identifiés du Cancéropôle Est :
Pr DENAT Franck
,
Dr GONCALVES Victor
Tous les auteurs :
Gourni E, Canovas C, Goncalves V, Denat F, Meyer PT, Maecke HR
Lien Pubmed
Résumé
The present study aims at developing and evaluating an urea-based prostate specific membrane antigen (PSMA) inhibitor suitable for labeling with 111In for SPECT and intraoperative applications as well as 68Ga and 64Cu for PET imaging.
Mots clés
Acetates, chemistry, Animals, Antigens, Surface, metabolism, Female, Gallium Radioisotopes, pharmacokinetics, Glutamate Carboxypeptidase II, metabolism, Heterocyclic Compounds, 1-Ring, chemistry, Humans, Image Processing, Computer-Assisted, Male, Mice, Mice, Inbred BALB C, Positron-Emission Tomography, Prostatic Neoplasms, diagnostic imaging, Radiopharmaceuticals, pharmacokinetics, Tissue Distribution, Tumor Cells, Cultured, Xenograft Model Antitumor Assays
Référence
PLoS ONE. 2015 ;10(12):e0145755