Fiche publication


Date publication

janvier 2015

Journal

PloS one

Auteurs

Membres identifiés du Cancéropôle Est :
Pr DENAT Franck , Dr GONCALVES Victor


Tous les auteurs :
Gourni E, Canovas C, Goncalves V, Denat F, Meyer PT, Maecke HR

Résumé

The present study aims at developing and evaluating an urea-based prostate specific membrane antigen (PSMA) inhibitor suitable for labeling with 111In for SPECT and intraoperative applications as well as 68Ga and 64Cu for PET imaging.

Mots clés

Acetates, chemistry, Animals, Antigens, Surface, metabolism, Female, Gallium Radioisotopes, pharmacokinetics, Glutamate Carboxypeptidase II, metabolism, Heterocyclic Compounds, 1-Ring, chemistry, Humans, Image Processing, Computer-Assisted, Male, Mice, Mice, Inbred BALB C, Positron-Emission Tomography, Prostatic Neoplasms, diagnostic imaging, Radiopharmaceuticals, pharmacokinetics, Tissue Distribution, Tumor Cells, Cultured, Xenograft Model Antitumor Assays

Référence

PLoS ONE. 2015 ;10(12):e0145755