Characterization of long non-coding RNA transcriptome in clear-cell renal cell carcinoma by next-generation deep sequencing.

Date publication

janvier 2015

Journal

Molecular oncology

Auteurs

Membres identifiés du Cancéropôle Est :
Pr MALOUF Gabriel

Tous les auteurs :
Malouf GG, Zhang J, Yuan Y, Compérat E, Rouprêt M, Cussenot O, Chen Y, Thompson EJ, Tannir NM, Weinstein JN, Valero V, Khayat D, Spano JP, Su X

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/25126716

Résumé

Long non-coding RNA (lncRNA) have proven to play key roles in cell physiology from nuclear organization and epigenetic remodeling to post-transcriptional regulation. Last decade, gene expression based-classifications have been developed in clear-cell renal cell carcinoma (ccRCC) to identify distinct subtypes of disease and predict patient's outcome. However, there are no current lncRNA comprehensive characterizations in ccRCC.

Mots clés

Adult, Aged, Aged, 80 and over, Carcinoma, Renal Cell, genetics, Databases, Nucleic Acid, Female, Gene Expression Regulation, Neoplastic, High-Throughput Nucleotide Sequencing, Humans, Kidney Neoplasms, genetics, Male, Middle Aged, Mutation, RNA, Long Noncoding, biosynthesis, RNA, Neoplasm, biosynthesis, Survival Rate

Référence

Mol Oncol. 2015 Jan;9(1):32-43