Impact of Procyanidins from Different Berries on Caspase 8 Activation in Colon Cancer.

Date publication

janvier 2015

Journal

Oxidative medicine and cellular longevity

Auteurs

Membres identifiés du Cancéropôle Est :
Dr MULLER Christian

Tous les auteurs :
Minker C, Duban L, Karas D, Järvinen P, Lobstein A, Muller CD

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/26180579

Résumé

The aim of this work is to identify which proapoptotic pathway is induced in human colon cancer cell lines, in contact with proanthocyanidins extracted from various berries.

Mots clés

Apoptosis, drug effects, Blueberry Plants, chemistry, Caspase 3, metabolism, Caspase 8, metabolism, Caspase 9, metabolism, Cell Line, Colonic Neoplasms, metabolism, DNA, metabolism, DNA Fragmentation, drug effects, Drug Resistance, Neoplasm, Fruit, chemistry, Humans, Phosphatidylserines, metabolism, Phosphorylation, drug effects, Plant Extracts, chemistry, Proanthocyanidins, chemistry, Receptors, TNF-Related Apoptosis-Inducing Ligand, metabolism, TNF-Related Apoptosis-Inducing Ligand, toxicity, Vaccinium vitis-idaea, chemistry, fas Receptor, metabolism, p38 Mitogen-Activated Protein Kinases, metabolism

Référence

Oxid Med Cell Longev. 2015 ;2015:154164