Insights in Nanoparticle-Bacterium Interactions: New Frontiers to Bypass Bacterial Resistance to Antibiotics.

Date publication

janvier 2015

Journal

Current pharmaceutical design

Auteurs

Membres identifiés du Cancéropôle Est :
Pr DUVAL Raphaël

Tous les auteurs :
Diab R, Khameneh B, Joubert O, Duval R

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/26420233

Résumé

Nanotechnology has been revealed as a fundamental approach for antibiotics delivery. In this paper, recent findings demonstrating the superiority of nanocarried-antibiotics over "naked" ones and the ways by which nanoparticles can help to overwhelm bacterial drug resistance are reviewed. The second part of this paper sheds light on nanoparticle-bacterium interaction patterns. Finally, key factors affecting the effectiveness of nanoparticles interactions with bacteria are discussed.

Mots clés

Animals, Anti-Bacterial Agents, administration & dosage, Bacteria, drug effects, Bacterial Infections, drug therapy, Drug Delivery Systems, Drug Resistance, Bacterial, Humans, Nanoparticles, Nanotechnology

Référence

Curr. Pharm. Des.. 2015 ;21(28):4095-105