Antimicrobial Photodynamic Therapy in the Nasal Decolonization of Maintenance Hemodialysis Patients: A Pilot Randomized Trial.

Fiche publication

Date publication

novembre 2022

Journal

American journal of kidney diseases : the official journal of the National Kidney Foundation

Auteurs

Membres identifiés du Cancéropôle Est :
Dr FROCHOT Céline

Tous les auteurs :
Bezerra DT, La Selva A, Cecatto RB, Deana AM, Prates RA, Bussadori SK, Mesquita Ferrari RA, Motta LJ, Santos Fernandes KP, Martimbianco AL, Frochot C, Pereira BJ, Rossi F, Mimica MJ, Ratto Tempestini Horliana AC

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/36396084

Résumé

Infections are an important cause of mortality among patients receiving maintenance hemodialysis. Staphylococcus aureus is a frequent etiological agent and previous nasal colonization is a risk factor for infection. Repeated antimicrobial decolonization reduces infection in this population but can induce resistance. We compared photodynamic therapy, a promising bactericidal treatment that does not induce resistance, to mupirocin treatment among nasal carriers of Staphylococcus aureus.