Fiche publication
Date publication
octobre 2013
Auteurs
Membres identifiés du Cancéropôle Est :
Dr BELLEMIN-LAPONNAZ Stéphane
Tous les auteurs :
Torres M, Maisse-Francois A, Bellemin-Laponnaz S
Résumé
Multitopic chiral copper complexes based on bis(oxazoline) have been applied in the enantioselective -hydrazination of -ketoesters. High yields and excellent enantioselectivities were obtained. Furthermore, the catalytic systems have been recovered in up to ten cycles without loss of activity or enantioselectivity. The formation of coordination polymers [polytopic ligand-Cu](n) has been confirmed by UV/Vis titrations. Significant metal leaching was observed on increasing the topicity of the ligand. The nature of the catalyst was studied by nonlinear effect experiments.
Référence
Chemcatchem. 2013 Oct;5(10):3078-85.
