An incidental finding of maternal multiple myeloma by non invasive prenatal testing.

Date publication

décembre 2017

Journal

Prenatal diagnosis

Auteurs

Membres identifiés du Cancéropôle Est :
Dr DORVAUX Véronique

Tous les auteurs :
Imbert-Bouteille M, Chiesa J, Gaillard JB, Dorvaux V, Altounian L, Gatinois V, Mousty E, Finge S, Bourquard P, Vermeesch JR, Legius E, Vandenberghe P

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/29023902

Résumé

What is already known about this subject? Non invasive prenatal testing for fetal trisomies 13, 18, and 21 occasionally identifies maternal cancer. What does this study add? A further case of maternal cancer incidentally diagnosed by routine NIPT. Extensive NIPT abnormalities are unlikely to be of fetal origin. Information given to patients should also adequately advise patients on potential incidental findings and might offer the option to opt out of receiving results beyond the trisomy report. International guidelines would improve patient counseling.

Mots clés

Adult, Female, Genetic Testing, Humans, Incidental Findings, Maternal Serum Screening Tests, Multiple Myeloma, diagnosis, Pregnancy, Pregnancy Complications, Neoplastic, diagnosis, Sequence Analysis, DNA

Référence

Prenat Diagn. 2017 12;37(12):1257-1260