Modified DCF (Docetaxel, Cisplatin and 5-fluorouracil) chemotherapy is effective for the treatment of advanced rectal squamous cell carcinoma.

Fiche publication

Date publication

novembre 2022

Journal

Frontiers in oncology

Auteurs

Membres identifiés du Cancéropôle Est :
Pr BORG Christophe , Dr VIENOT Angélique , Dr KIM Stephano , Dr LAKKIS Zaher , Dr BOUSTANI Jihane

Tous les auteurs :
Hervé L, Kim S, Boustani J, Klajer E, Pernot M, Nguyen T, Lakkis Z, Borg C, Vienot A

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/36465395

Résumé

Advanced rectal squamous cell carcinoma (rSCC) is a very rare and aggressive entity, and the best initial management is crucial for long survival as well as organ preservation and quality of life. Whereas local diseases are treated with chemo-radiotherapy and salvage surgery, data are scarce on how to treat more advanced diseases, and the role of induction chemotherapy is unknown.