Acute skin toxicity of conventional fractionated versus hypofractionated radiotherapy in breast cancer patients receiving regional node irradiation: the real-life prospective multicenter HYPOBREAST cohort.

Date publication

décembre 2022

Journal

BMC cancer

Auteurs

Membres identifiés du Cancéropôle Est :
Dr CLAVIER Jean-Baptiste , Dr DESANDES Emmanuel , Dr GUIHARD Sébastien , Pr PEIFFERT Didier , Dr FAIVRE Jean-Christophe

Tous les auteurs :
Bruand M, Salleron J, Guihard S, Crety CM, Liem X, Pasquier D, Lamrani-Ghaouti A, Charra-Brunaud C, Peiffert D, Clavier JB, Desandes E, Faivre JC

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/36526987

Résumé

Large-scale trials have shown that hypofractionated adjuvant breast radiotherapy was as effective in terms of survival and local control as conventional fractionated radiotherapy, and acute toxicity was reduced with hypofractionated radiotherapy. However, there is a lack of data about the toxicity of breast with regional nodal irradiation (RNI). The aim of this study was to assess the effect of fractionation on radiation-related acute skin toxicity in patients receiving RNI in addition to whole-breast or chest wall irradiation, using real-life data.

Mots clés

Adjuvant radiotherapy, Breast neoplasms, Conformal radiotherapy, Hypofractionation, Intensity-modulated, Observational study, Prospective studies, Radiation dose, Radiotherapy, Radiotherapy dose fractionation

Référence

BMC Cancer. 2022 12 16;22(1):1318