Fiche publication


Date publication

janvier 2023

Journal

Journal of clinical medicine

Auteurs

Membres identifiés du Cancéropôle Est :
Pr RAMANAH Rajeev


Tous les auteurs :
De Gracia S, Fatton B, Cosson M, Campagne-Loiseau S, Ferry P, Lucot JP, Debodinance P, Panel L, Deffieux X, Garbin O, Lamblin G, Carlier-Guérin C, Ramanah R, Fauconnier A, Serrand C, Fritel X, de Tayrac R

Résumé

To evaluate the rates of serious complications and reoperation for recurrence following sacrospinous ligament fixation (SSLF) for apical pelvic organ prolapse. This was a national registry ancillary cohort comparative study. The VIGI-MESH registry includes data from 24 French health centers prospectively collected between May 2017 and September 2021. Time to occurrence of a serious complication or reoperation for genital prolapse recurrence was explored using the Kaplan-Meier curve and Log-rank test. The inverse probability of treatment weighting, based on propensity scores, was used to adjust for between-group differences. A total of 1359 women were included and four surgical groups were analyzed: Anterior SSLF with mesh (n = 566), Anterior SSLF with native tissue (n = 331), Posterior SSLF with mesh (n = 57), and Posterior SSLF with native tissue (n = 405). Clavien-Dindo Grade III complications or higher were reported in 34 (2.5%) cases, with no statistically significant differences between the groups. Pelvic organ prolapse recurrence requiring re-operation was reported in 44 (3.2%) women, this was higher following posterior compared with anterior SSLF ( = 0.0034). According to this large database ancillary study, sacrospinous ligament fixation is an effective and safe surgical treatment for apical prolapse. The different surgical approaches (anterior/posterior and with/without mesh) have comparable safety profiles. However, the anterior approach and the use of mesh were associated with a lower risk of reoperation for recurrence compared with the posterior approach and the use of native tissue, respectively.

Mots clés

apical prolapse, mesh repair, native tissue repair, pelvic organ prolapse, pelvic organ prolapse recurrence, sacrospinous ligament fixation, surgical complication, vaginal approach

Référence

J Clin Med. 2023 01 6;12(2):