Early exposure to farm dust in an allergic airway inflammation rabbit model: Does it affect bronchial and cough hyperresponsiveness?

Date publication

janvier 2023

Journal

PloS one

Auteurs

Membres identifiés du Cancéropôle Est :
Pr MAUNY Frédéric

Tous les auteurs :
Divaret-Chauveau A, Foucaud L, Demoulin B, Teston C, Loison P, Le Cann P, Schweitzer C, De Carvalho Bittencourt M, Mauny F, Demoulin-Alexikova S

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/36706084

Résumé

Over the past 50 years, the prevalence of allergic respiratory diseases has been increasing. The Hygiene hypothesis explains this progression by the decrease in the bio-diversity of early microbial exposure. This study aims to evaluate the effect of early-life farm exposure on airway hyperresponsiveness and cough hypersensitivity in an allergic airway inflammation rabbit model.

Référence

PLoS One. 2023 01 27;18(1):e0279498