Leukocyte cell population data in patients with cardiac surgery and cardiopulmonary bypass: A potential readily available tool to monitor immunity.

Fiche publication

Date publication

janvier 2023

Journal

Frontiers in immunology

Auteurs

Membres identifiés du Cancéropôle Est :
Pr MASSON David

Tous les auteurs :
Nguyen M, Stiel L, Guilloteau A, Bahr PA, Masson D, Thomas C, Blot M, Guy J, Fontaine C, Durand B, Bouhemad B, Guinot PG

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/36741408

Résumé

Cardiac surgery with cardiopulmonary bypass triggers sterile inflammation that is responsible for post-operative morbidity. Automated flow cytometry devices used for leucocyte count provide cell population data (CPD) regarding fluorescence intensity, size and granularity of leukocytes that have never been studied in the context of sterile inflammation. Our objective was to explore leukocyte cell population data in patients undergoing cardiac surgery with cardiopulmonary bypass in order to determine whether CPD could be used to monitor immune cell activation.