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Date publication

février 2023

Journal

Analytical chemistry

Auteurs

Membres identifiés du Cancéropôle Est :
Dr BUACHE Emilie , Dr GOBINET Cyril , Pr MORJANI Hamid , Pr PIOT Olivier


Tous les auteurs :
Goffin N, Buache E, Charpentier C, Lehrter V, Morjani H, Gobinet C, Piot O

Résumé

Cell heterogeneity is a crucial parameter for understanding the complexity of numerous biomedical issues. Trajectory inference-based approaches are recent tools developed for single-cell transcriptomics (scRNA-seq) data analysis. They aim to reconstruct evolving pathways from the variety of cell states that coexist simultaneously in a cell population. We propose to expand this concept to Raman spectroscopy, a label-free modality that probes the global molecular nature of a sample, by investigating the dynamics of adipocyte differentiation.

Référence

Anal Chem. 2023 02 14;: