Fiche publication


Date publication

janvier 2021

Journal

Crohn's & colitis 360

Auteurs

Membres identifiés du Cancéropôle Est :
Pr PEYRIN-BIROULET Laurent


Tous les auteurs :
Solitano V, D'Amico F, Da Rio L, Peyrin-Biroulet L, Danese S

Résumé

With the expiration of biologics' patents, biosimilars entered the market as a promising opportunity to reduce health-care costs in the field of inflammatory bowel diseases. Although biosimilars were initially poorly accepted, the growing evidence about their efficacy and safety has changed this situation, resulting in their widespread use. However, there is still an unmet need of improving patients' education about biosimilars to minimize nocebo responses and to accept nonmedical switching. Looking to the future, the use of recently authorized adalimumab biosimilars and the first attempts of adopting different strategies of switching (eg, cross-, multiple-) will fill some residual knowledge gaps.

Mots clés

Europe, biosimilars, inflammatory bowel diseases, switching

Référence

Crohns Colitis 360. 2021 01;3(1):otab012