Persistent deficiency of mucosal-associated invariant T cells during dermatomyositis.

Date publication

septembre 2020

Journal

Rheumatology (Oxford, England)

Auteurs

Membres identifiés du Cancéropôle Est :
Pr BENSUSSAN Armand

Tous les auteurs :
Cassius C, Branchtein M, Battistella M, Amode R, Lepelletier C, Jachiet M, de Masson A, Frumholtz L, Chasset F, Amoura Z, Mathian A, Samri A, Monfort JB, Bachmeyer C, Bengoufa D, Cordoliani F, Bagot M, Bensussan A, Bouaziz JD, Le Buanec H

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/31846040

Résumé

Mucosal-associated invariant T (MAIT) cells are innate-like lymphocytes that are important for antibacterial immunity and may have regulatory roles. MAIT cells are decreased during SLE. However, their frequencies and phenotype have not been investigated in DM. We studied MAIT cell frequencies and phenotype in DM patients with active and inactive disease (after treatment).

Mots clés

T-lymphocytes, autoimmunity, dermatomyositis, immunology, mucosal-associated invariant T cells

Référence

Rheumatology (Oxford). 2020 09 1;59(9):2282-2286