Fiche publication


Date publication

juin 2018

Journal

Journal of reproductive immunology

Auteurs

Membres identifiés du Cancéropôle Est :
Pr BENSUSSAN Armand


Tous les auteurs :
Lédée N, Prat-Ellenberg L, Petitbarat M, Chevrier L, Simon C, Irani EE, Vitoux D, Bensussan A, Chaouat G

Résumé

Corticotherapy is the leading medication worldwide for patients with history of repeated implantation failures (RIF) after IVF/ICSI. Nevertheless, we still do not know its local mechanism of action, hence its precise indication. Our objective is to document the impact of prednisone on the endometrial expression of immune biomarkers (CD56 cells count, IL-18/TWEAK, IL-15/Fn-14 mRNA ratio) at the time of uterine receptivity in a RIF population.

Mots clés

Corticoids, Endometrium, IVF/ICSI, Implantation failures, Uterine receptivity

Référence

J Reprod Immunol. 2018 06;127:11-15