Fiche publication


Date publication

janvier 2023

Journal

Research and practice in thrombosis and haemostasis

Auteurs

Membres identifiés du Cancéropôle Est :
Dr MANGIN Pierre


Tous les auteurs :
Angénieux C, Couvidou A, Brouard N, Eckly A, Dupuis A, Mangin PH, Maître B

Résumé

The platelet population is heterogeneous, with different subsets that differ on the basis of their function and reactivity. An intrinsic factor participating in this difference of reactivity could be the platelet age. The lack of relevant tools allowing a formal identification of young platelets prevents so far to draw solid conclusions regarding platelet reactivity. We recently reported that human leukocyte antigen-I (HLA-I) molecules are more expressed on human young platelets.

Mots clés

COAT, COllagen And Thrombin activated, CRP, Collagen Related Peptide, Conv, Convulxin, FC, Flow Cytometry, HLA-I, Human Leukocyte Antigen-I, P ribo prot, Anti-ribosomal P protein, TO, Thiazole orange, TRAP, Thrombin receptor activating peptide, electron microscopy, fluorescence-activated cell sorting, human class I antigens, platelets, procoagulant, vWF, Von Willebrand factor

Référence

Res Pract Thromb Haemost. 2023 01;7(1):100006