Fiche publication
Date publication
mai 2023
Journal
Histopathology
Auteurs
Membres identifiés du Cancéropôle Est :
Pr CRIBIER Bernard
Tous les auteurs :
Kervarrec T, Pissaloux D, Paindavoine S, Tirode F, Osio A, Mourah S, Jouenne F, Sohier P, Calonje E, Pekar A, Luna EVE, Goto K, Delalande F, Frouin E, Macagno N, Drouot F, Faisan M, Cribier B, Battistella M, de la Fouchardière A
Lien Pubmed
Résumé
Poroma is a benign adnexal neoplasm with differentiation towards the upper portion of the sweat gland apparatus. In 2019, Sekine et al. demonstrated recurrent YAP1::MAML2 and YAP1::NUTM1 fusion in poroma and porocarcinoma. Follicular, sebaceous and/or apocrine differentiation has been reported in rare cases of poroma and whether these tumours constitute a variant of poroma or represent a distinctive tumour is a matter to debate. Herein we describe the clinical, immunophenotypic, and molecular features of 13 cases of poroma with folliculo-sebaceous differentiation.
Mots clés
PAK2, apocrine poroma, folliculo-sebaceous differentiation, holocrine poroma, infundibular adenoma
Référence
Histopathology. 2023 05 18;:
