Impact of age on survival according to molecular tumor findings in children and adolescents with soft-tissue and bone sarcoma: The BIOSCA project.

Fiche publication

Date publication

juin 2023

Journal

Cancer epidemiology

Auteurs

Membres identifiés du Cancéropôle Est :
Dr DESANDES Emmanuel , Dr LACOUR Brigitte

Tous les auteurs :
Desandes E, Lapouble E, Lacour B, Guissou S, Goujon S, Defachelles AS, Marechal V, Gaspar N, Gomez-Mascard A, Karanian M, Marec-Berard P, Minard-Colin V, Orbach D, Tabone MD, Delattre O, Pierron G

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/37357067

Résumé

Adolescents (15-19 years) with sarcoma are known to have significantly worse survival than children (0-14 years). One possible reason may be that the adolescent sarcomas exhibit specific biological characteristics resulting in differences in clinical presentation and treatment resistance behaviors. The BIOSCA project aims to further explore these age-related differences in survival accounting for molecular tumor characteristic in children and adolescents with sarcoma.