Increased gut permeability and intestinal inflammation precede arthritis onset in the adjuvant-induced model of arthritis.

Fiche publication

Date publication

juin 2023

Journal

Arthritis research & therapy

Auteurs

Membres identifiés du Cancéropôle Est :
Dr PAIS DE BARROS Jean-Paul , Pr HOCQUET Didier

Tous les auteurs :
Hecquet S, Totoson P, Martin H, Algros MP, Saas P, Pais-de-Barros JP, Atchon A, Valot B, Hocquet D, Tournier M, Prati C, Wendling D, Demougeot C, Verhoeven F

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/37280714

Résumé

Intestinal inflammation, dysbiosis, intestinal permeability (IP), and bacterial translocation (BT) have been identified in patients with spondyloarthritis but the time at which they appear and their contribution to the pathogenesis of the disease is still a matter of debate.