CroMaSt: a workflow for assessing protein domain classification by cross-mapping of structural instances between domain databases and structural alignment.

Date publication

juin 2023

Journal

Bioinformatics advances

Auteurs

Membres identifiés du Cancéropôle Est :
Dr DEVIGNES Marie-Dominique

Tous les auteurs :
Dhondge H, Chauvot de Beauchêne I, Devignes MD

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/37431435

Résumé

Protein domains can be viewed as building blocks, essential for understanding structure-function relationships in proteins. However, each domain database classifies protein domains using its own methodology. Thus, in many cases, domain models and boundaries differ from one domain database to the other, raising the question of domain definition and enumeration of true domain instances.

Référence

Bioinform Adv. 2023 06 27;3(1):vbad081