Fiche publication


Date publication

août 2023

Journal

Seminars in musculoskeletal radiology

Auteurs

Membres identifiés du Cancéropôle Est :
Pr GILLET Pierre


Tous les auteurs :
Gillet R, Boubaker F, Hossu G, Thay A, Gillet P, Blum A, Teixeira PAG

Résumé

Bone microarchitecture has several clinical implications over and above estimating bone strength. Computed tomography (CT) analysis mainly uses high-resolution peripheral quantitative CT and micro-CT, research imaging techniques, most often limited to peripheral skeleton assessment. Ultra-high-resolution (UHR) CT and photon-counting detector CT, two commercially available techniques, provide images that can approach the spatial resolution of the trabeculae, bringing bone microarchitecture analysis into clinical practice and improving depiction of bone vascularization, tumor matrix, and cortical and periosteal bone. This review presents bone microarchitecture anatomy, principles of analysis, reference measurements, and an update on the performance and potential clinical applications of these new CT techniques. We also share our clinical experience and technical considerations using an UHR-CT device.

Mots clés

Humans, Tomography, X-Ray Computed, Cancellous Bone, Radiopharmaceuticals

Référence

Semin Musculoskelet Radiol. 2023 08;27(4):397-410