Fiche publication


Date publication

décembre 2023

Journal

Annales d'endocrinologie

Auteurs

Membres identifiés du Cancéropôle Est :
Pr PETIT Jean-Michel , Pr VERGES Bruno , Pr SCHMITT Antonin


Tous les auteurs :
Spanjaard P, Petit JM, Schmitt A, Vergès B, Bouillet B

Résumé

Inhibitors of mTOR (mTORi) are frequently used as anticancer treatment. They were responsible for metabolic side-effects in phase 3 studies, which provided only an incomplete picture of these metabolic complications. The aim of our study was therefore to evaluate, in a real-life setting, outcomes for patients with dyslipidemia or diabetes under mTORi, and the incidence and management of metabolic abnormalities occurring under mTORi in the absence of known metabolic history.

Mots clés

diabetes, dyslipidemia, mTOR inhibitors, metabolic complications

Référence

Ann Endocrinol (Paris). 2023 12 1;: