Immune changes in hilar tumor draining lymph nodes following node sparing neoadjuvant chemoradiotherapy of localized cN0 non-small cell lung cancer.

Fiche publication

Date publication

novembre 2023

Journal

Frontiers in oncology

Auteurs

Membres identifiés du Cancéropôle Est :
Dr MARTIN Etienne , Dr PAGES Pierre-Benoit

Tous les auteurs :
Khalifa J, Thébault N, Scarlata CM, Norkowski E, Massabeau C, Brouchet L, Peries Bataille S, Casaroli C, Vaz L, Valle C, Sarot E, Saint-Laurent N, Martin E, Pages PB, Millière A, Mazières J, Cohen-Jonathan Moyal E, Lauzéral-Vizcaïno F, Ayyoub M

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/38074683

Résumé

While much progress has been accomplished in the understanding of radiation-induced immune effects in tumors, little is known regarding the mechanisms involved at the tumor draining lymph node (TDLN) level. The objective of this retrospective study was to assess the immune and biological changes arising in non-involved TDLNs upon node sparing concurrent chemoradiotherapy (CRT) of non-small cell lung cancer (NSCLC) tumors.