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Date publication

novembre 2023

Journal

Fundamental & clinical pharmacology

Auteurs

Membres identifiés du Cancéropôle Est :
Pr JOUZEAU Jean-Yves


Tous les auteurs :
Brenkman M, Cartau T, Pape E, Kolodziej A, Charmillon A, Novy E, Jouzeau JY, Gambier N, Scala-Bertola J

Résumé

Beta-lactam antibiotics are reported for some of them to be subject to a rapid degradation in infusion solutions and in human blood samples. However, the current data of stability available in blood samples are limited to a few number of beta-lactam antibiotics, and the methodology of the corresponding studies may be discussed. The objective of the present study is to evaluate the stability of 10 beta-lactam antibiotics in human plasma samples.

Mots clés

beta-lactams, drug monitoring, human plasma, quality assurance, stability

Référence

Fundam Clin Pharmacol. 2023 11 20;: