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Date publication

janvier 2024

Journal

Journal of cachexia, sarcopenia and muscle

Auteurs

Membres identifiés du Cancéropôle Est :
Pr PIVOT Xavier , Dr SCHOTT Roland , Dr BENDER Laura , Pr FAVRET Fabrice , Pr GENY Bernard , Dr HUCTEAU Elyse , Dr MALLARD Joris


Tous les auteurs :
Mallard J, Hucteau E, Bender L, Moinard-Butot F, Rochelle E, Boutonnet L, Grandperrin A, Schott R, Pflumio C, Trensz P, Kalish-Weindling M, Charles AL, Gény B, Favret F, Pivot X, Hureau TJ, Pagano AF

Résumé

Breast cancer patients are commonly treated with sequential administrations of epirubicin-cyclophosphamide (EC) and paclitaxel (TAX). The chronic effect of this treatment induces skeletal muscle alterations, but the specific effect of each chemotherapy agent is unknown. This study aimed to investigate the effect of EC or TAX administration on skeletal muscle homeostasis in breast cancer patients.

Mots clés

Anthracycline-cyclophosphamide, Mitochondria, Mitochondrial respiration, Muscle biopsies, Skeletal muscle deconditioning, Taxanes

Référence

J Cachexia Sarcopenia Muscle. 2024 01 6;: