Fiche publication


Date publication

janvier 2024

Journal

Journal of vascular research

Auteurs

Membres identifiés du Cancéropôle Est :
Pr GILLERY Philippe


Tous les auteurs :
Doué M, Marques G, Okwieka A, Gorisse L, Piétrement C, Gillery P, Jaisson S

Résumé

Carbamylation is a nonenzymatic post-translational modification of proteins characterized by the binding of isocyanic acid to amino groups of proteins, which leads to the alteration of their properties. An increase in serum carbamylation-derived products, including homocitrulline (HCit), has been shown to be associated with the development of cardiovascular diseases.

Mots clés

Abdominal aortic aneurysm, Carbamylation, Cardiovascular diseases, Homocitrulline, Nonenzymatic post-translational modifications

Référence

J Vasc Res. 2024 01 19;:1-8