Fiche publication
Date publication
janvier 1995
Journal
Comptes rendus des seances de la Societe de biologie et de ses filiales
Auteurs
Membres identifiés du Cancéropôle Est :
Pr BASTIE Jean-Noël
,
Dr DELVA Laurent
,
Dr GUIDEZ Fabien
Tous les auteurs :
Chomienne C, Guidez F, Micléa JM, Bastie JN, Delva L, Rousselot P, Ballerini P
Lien Pubmed
Résumé
Differentiation of the hematopoietic tissue is controlled by growth factors which act precisely on stem cells arriving at a specific stage of differentiation. The recent identification of retinoic acid, a vitamin A metabolite, as an active differentiating agent of acute promyelocytic leukemia, has allowed to define a normal group of growth and differentiation factors of the myeloid tissue: vitamins A and B and thyroid hormones.
Mots clés
Cell Differentiation, drug effects, Cholecalciferol, pharmacology, Embryology, HL-60 Cells, pathology, Hematopoietic Stem Cells, cytology, Humans, Keratolytic Agents, pharmacology, Receptors, Cytoplasmic and Nuclear, genetics, Receptors, Thyroid Hormone, genetics, Tretinoin, pharmacology
Référence
C R Seances Soc Biol Fil. 1995 ;189(4):493-501
