Impact of breast surgical procedure on survival in BRCA mutated patients with invasive breast cancer: mastectomy versus conservative treatment.

Fiche publication

Date publication

février 2024

Journal

Journal of gynecology obstetrics and human reproduction

Auteurs

Membres identifiés du Cancéropôle Est :
Pr COUTANT Charles , Dr DABAKUYO-YONLI Sandrine

Tous les auteurs :
Mahiou K, Jankowski C, Vincent L, Costaz H, Padeano MM, Mamguem A, Dabakuyo S, Coutant C

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/38428460

Résumé

Patients with BRCA1/2 mutations have a higher risk of developing breast cancer compared to the wild-type population. For patients with a BRCA mutation, there are no specific recommendations for surgical management. The aim of this study was therefore to retrospectively investigate overall survival (OS) and recurrence-free survival (RFS) of BRCA mutated patients with localized invasive breast cancer, by comparing conservative surgery versus mastectomy.