Fiche publication


Date publication

mai 2024

Journal

Heliyon

Auteurs

Membres identifiés du Cancéropôle Est :
Pr ROSSIGNOL Patrick


Tous les auteurs :
Leierer J, Salib M, Evgeniou M, Rossignol P, Massy ZA, Kratochwill K, Mayer G, Fellström B, Girerd N, Zannad F, Perco P

Résumé

Statins are widely used to reduce the risk of cardiovascular disease (CVD). Patients with end-stage renal disease (ESRD) on hemodialysis have significantly increased risk of developing CVD. Statin treatment in these patients however did not show a statistically significant benefit in large trials on a patient cohort level.

Mots clés

AURORA cohort, Cardiovascular risk, Cox proportional hazards regression models, Gene expression profiling, Hemodialysis, Patient stratification, Predictive biomarkers, Statins

Référence

Heliyon. 2024 05 15;10(9):e30709