Fiche publication
Date publication
mai 2024
Journal
Frontiers in molecular neuroscience
Auteurs
Membres identifiés du Cancéropôle Est :
Dr GOUMON Yannick
Tous les auteurs :
Reho G, Menger Y, Goumon Y, Lelièvre V, Cadiou H
Lien Pubmed
Résumé
Pain mostly arises because specialized cells called nociceptors detect harmful or potentially harmful stimuli. In lower animals with less convoluted nervous system, these responses are believed to be purely nociceptive. Amongst invertebrate animal models, planarians are becoming popular in a wide range of pharmacological and behavioral studies beyond the field of regeneration. Recent publications led the way on pain studies by focusing on nociceptive behaviors such as the 'scrunching' gait displayed under various noxious stimuli, as opposed to the 'gliding' gait planarians usually adopt in normal conditions.
Mots clés
NSAID, RNA interference, TRPA1, meloxicam, morphine, nociception, planarians
Référence
Front Mol Neurosci. 2024 05 1;17:1368009
