Interference With VIP to Distinguish Between Real and False VIPoma: National Study From the French Endocrine Tumors Group.

Fiche publication

Date publication

mai 2024

Journal

Journal of the Endocrine Society

Auteurs

Membres identifiés du Cancéropôle Est :
Pr LEPAGE Côme

Tous les auteurs :
Chevalier B, Bonnet D, Lepage C, Perrier M, Borson-Chazot F, Abeillon J, Delobel JB, Jannin A, Hadoux J, Haissaguere M, Lombard-Bohas C, Walter T, Chardon L

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/38854908

Résumé

Vasoactive intestinal peptide (VIP)-secreting tumors (VIPomas) are digestive neuroendocrine tumors in which the hormonal secretion is life-threatening. Biological confirmation is obtained by demonstrating an elevation in plasma VIP, usually using radioimmunoassay (RIA). In some cases, analytical interference is suspected. We developed 3 different techniques to detect interference in VIP RIA.