Fiche publication


Date publication

juin 2024

Journal

Diagnostic pathology

Auteurs

Membres identifiés du Cancéropôle Est :
Pr BORG Christophe , Mr MONNIEN Franck , Dr LAKKIS Zaher , Dr SELMANI Zohair , Pr BIBEAU Frédéric , Dr MOLIMARD Chloé


Tous les auteurs :
D'Angelo F, Monnien F, Overs A, Pem I, Dor F, Abad M, Felix S, Selmani Z, Lakkis Z, Borg C, Doussot A, Bibeau F, Molimard C

Résumé

HER2-targeted therapies have recently emerged as an option in the management of metastatic colorectal cancer (mCRC) overexpressing HER2. However, data regarding HER2 status in primary CRC and its corresponding liver metastases are limited, potentially influencing clinical decisions. Therefore, the aim of this study was to compare the HER2 status in primary CRC and paired liver metastases.

Mots clés

Colorectal cancer, HER2, Liver metastasis, Tumor heterogeneity

Référence

Diagn Pathol. 2024 06 22;19(1):88