Fiche publication


Date publication

août 2024

Journal

British journal of haematology

Auteurs

Membres identifiés du Cancéropôle Est :
Dr PAGLIUCA Simona


Tous les auteurs :
Gurnari C, Lima ACM, Pagliuca S

Résumé

HLA loss represents the result of immune forces shaping bone marrow clonal dynamics in immune aplastic anaemia. Human leukocyte antigen (HLA)-deficient clones may rescue haematopoiesis by evading immune attacks, potentially guiding treatment strategies. Commentary on: Zaimoku et al. Haematopoietic regeneration by HLA-A*0206-deficient clones in severe aplastic anaemia without definitive immunosuppressive treatment. Br J Haematol 2024 (Online ahead of print). doi: 10.1111/bjh.19712.

Mots clés

aplastic anaemia, clonal haematopoiesis, haematopoietic stem cells, immune suppressive treatment

Référence

Br J Haematol. 2024 08 26;: