Interrelationships between the kinetics of VLDL subspecies and HDL catabolism in abdominal obesity: a multicenter tracer kinetic study.

Date publication

novembre 2014

Journal

The Journal of clinical endocrinology and metabolism

Auteurs

Membres identifiés du Cancéropôle Est :
Pr DUVILLARD Laurence , Pr VERGES Bruno

Tous les auteurs :
Vergès B, Adiels M, Boren J, Barrett PH, Watts GF, Chan D, Duvillard L, Söderlund S, Matikainen N, Kahri J, Robin I, Taskinen MR

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/25077901

Résumé

Low plasma high-density lipoprotein (HDL) cholesterol is a major abnormality in abdominal obesity. This relates due to accelerated HDL catabolism, but the underlying mechanism requires further elucidation. The relationships between HDL catabolism and other variables that may be modified in abdominal obesity, such as very low-density lipoprotein (VLDL) subspecies (VLDL1, VLDL2) kinetics, liver fat, or visceral adiposity, remain to be investigated.

Mots clés

Adipose Tissue, metabolism, Adult, Aged, Apolipoproteins, metabolism, Female, Humans, Lipoproteins, HDL, metabolism, Lipoproteins, VLDL, metabolism, Liver, metabolism, Male, Middle Aged, Obesity, Abdominal, metabolism

Référence

J. Clin. Endocrinol. Metab.. 2014 Nov;99(11):4281-90