Zinc-alpha2-glycoprotein modulates blood pressure by regulating renal lipid metabolism reprogramming - mediated urinary Na+ excretion in hypertension.

Fiche publication

Date publication

septembre 2024

Journal

Cardiovascular research

Auteurs

Membres identifiés du Cancéropôle Est :
Pr SCHINI-KERTH Valérie

Tous les auteurs :
Zhou X, Deng C, Chen L, Lei L, Wang X, Zheng S, Chen C, Du C, Schini-Kerth VB, Yang J

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/39253990

Résumé

Organs modulating blood pressure are associated with a common cytokine known as adipokines. We chose Zinc-alpha2-glycoprotein (ZAG) due to its prioritized transcriptional level in the database. Previous studies showed that ZAG is involved in metabolic disorders. The aim of this study was to investigate its role in hypertension.