Fiche publication
Date publication
septembre 2024
Journal
Expert opinion on drug metabolism & toxicology
Auteurs
Membres identifiés du Cancéropôle Est :
Pr PEYRIN-BIROULET Laurent
Tous les auteurs :
Vieujean S, Peyrin-Biroulet L
Lien Pubmed
Résumé
Ulcerative colitis is a chronic inflammatory bowel disease, affecting the colorectal mucosae, with a relapsing-remitting course, characterized by the trafficking and gathering of lymphocytes in the inflammatory intestinal mucosa. Sphingosine-1-phosphate (S1P) receptor modulators preventing lymphocytes egress from lymphoid tissues to the active inflammation site is an alternative therapeutic option in this condition.
Mots clés
Etrasimod, Ozanimod, Pharmacokinetics, Sphingosine-1-phosphate receptor modulators, VTX002, ulcerative colitis
Référence
Expert Opin Drug Metab Toxicol. 2024 09 9;:
