Prevalence of Escherichia coli sequence type 131 and its H30 subclone among E. coli isolates in a French hospital.

Fiche publication

Date publication

novembre 2014

Journal

International journal of antimicrobial agents

Auteurs

Membres identifiés du Cancéropôle Est :
Pr HOCQUET Didier

Tous les auteurs :
Lafolie J, Nicolas-Chanoine MH, Grenouillet F, Hocquet D, Bertrand X

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/25241262

Résumé

The prevalence of Escherichia coli sequence type 131 (ST131) and its subclone H30 was assessed among a collection of 490 E. coli isolated in 2013 in a French university hospital. The prevalence of ST131 was 4% among bloodstream isolates (regardless of antimicrobial resistance) and 17.2% among extended-spectrum β-lactamase (ESBL)-producing isolates. Although a much lower prevalence of ST131 was found among bloodstream E. coli isolates compared with other countries, a large predominance of H30 subclone within ST131 was confirmed. It was also confirmed that, among ESBL-producing E. coli, ST131 isolates were more frequently resistant to amoxicillin/clavulanic acid, ceftazidime, fluoroquinolones and aminoglycosides than non-ST131 isolates.