Fiche publication
Date publication
septembre 2024
Journal
Biochimica et biophysica acta. Molecular basis of disease
Auteurs
Membres identifiés du Cancéropôle Est :
Pr VERGELY Catherine
,
Dr COLLIN Bertrand
Tous les auteurs :
Josse M, Rigal E, Rosenblatt-Velin N, Collin B, Dogon G, Rochette L, Zeller M, Vergely C
Lien Pubmed
Résumé
Cardiovascular (CV) pathologies remain a leading cause of death worldwide, often associated with common comorbidities such as overweight, obesity, type 2 diabetes or hypertension. An innovative mouse model of metabolic syndrome induced by postnatal overfeeding (PNOF) through litter size reduction after birth was developed experimentally. This study aimed to evaluate the impact of PNOF on cardiac remodelling and the development of heart failure following myocardial infarction.
Mots clés
Echocardiography, Heart failure, Myocardial infarction, Postnatal overfeeding, Rodents
Référence
Biochim Biophys Acta Mol Basis Dis. 2024 09 18;:167516
