The comprehensive complication index: a novel and more sensitive endpoint for assessing outcome and reducing sample size in randomized controlled trials.

Date publication

novembre 2014

Journal

Annals of surgery

Auteurs

Membres identifiés du Cancéropôle Est :
Pr PESSAUX Patrick

Tous les auteurs :
Slankamenac K, Nederlof N, Pessaux P, de Jonge J, Wijnhoven BP, Breitenstein S, Oberkofler CE, Graf R, Puhan MA, Clavien PA

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/25379846

Résumé

To test whether the newly developed comprehensive complication index (CCI) is more sensitive than traditional endpoints for detecting between-group differences in randomized controlled trials (RCTs).

Mots clés

Diverticulitis, Colonic, surgery, Endpoint Determination, methods, Esophageal Neoplasms, surgery, Europe, Humans, Pancreatic Diseases, surgery, Postoperative Complications, classification, Randomized Controlled Trials as Topic, Research Design, Sample Size, Sensitivity and Specificity

Référence

Ann. Surg.. 2014 Nov;260(5):757-62; discussion 762-3