Fiche publication
Date publication
novembre 2014
Journal
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
Auteurs
Membres identifiés du Cancéropôle Est :
Pr PEYRIN-BIROULET Laurent
Tous les auteurs :
Jess T, Lopez A, Andersson M, Beaugerie L, Peyrin-Biroulet L
Lien Pubmed
Résumé
Patients with inflammatory bowel disease (IBD) are at increased risk for developing colorectal neoplasia. Researchers have debated whether treatment of IBD with thiopurines reduces cancer risk. We performed a meta-analysis of thiopurine exposure and risk of colorectal dysplasia or cancer in patients with IBD.
Mots clés
Colorectal Neoplasms, epidemiology, Humans, Immunosuppressive Agents, therapeutic use, Inflammatory Bowel Diseases, complications, Mercaptopurine, therapeutic use, Risk Assessment, Treatment Outcome
Référence
Clin. Gastroenterol. Hepatol.. 2014 Nov;12(11):1793-1800.e1