Clinical impact of large genomic explorations at diagnosis in 198 pediatric solid tumors: a monocentric study aiming practical feasibility of precision oncology.

Fiche publication

Date publication

octobre 2024

Journal

BMC cancer

Auteurs

Membres identifiés du Cancéropôle Est :
Pr ENTZ-WERLE Natacha , Dr GUERIN Eric , Dr LINDNER Véronique , Dr JANNIER Sarah , Dr LHERMITTE Benoît , Dr REITA Damien , Dr DESCHUYTER Marlène

Tous les auteurs :
Simon J, Reita D, Guerin E, Lhermitte B, Weingertner N, Lefebvre F, Karanian M, Masliah-Planchon J, Lindner V, Onea A, Jannier S, Salmon A, Bergthold G, Vincent F, Deschuyter M, Barbaza MO, Entz-Werlé N

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/39433989

Résumé

Faced to the growing development of collecting systematic molecular analyses in relapsed pediatric cancers to transform their targeted matched therapies, this study aimed to assess the clinical and therapeutic indications of systematic diagnostic genomic explorations performed in pediatric solid cancers to determine which type of screening and if it afford at relapse time an accurate targeted strategy.