Fiche publication
Date publication
octobre 2014
Journal
PloS one
Auteurs
Membres identifiés du Cancéropôle Est :
Pr BENSUSSAN Armand
Tous les auteurs :
Rahmati M, Petitbarat M, Dubanchet S, Bensussan A, Chaouat G, Ledee N
Lien Pubmed
Résumé
Recombinant human Granulocyte-Colony Stimulating Factor (rhG-CSF) supplementation seems to be a promising innovative therapy in reproductive medicine, used in case of recurrent miscarriage, embryo implantation failure or thin endometrium, although its mechanisms of action remain unknown. Our aim was to identify possible endometrial pathways influenced by rhG-CSF.
Mots clés
Abortion, Habitual, genetics, Adult, CD40 Antigens, genetics, CD40 Ligand, genetics, Embryo Implantation, drug effects, Endometrium, metabolism, Female, Gene Expression Regulation, drug effects, Granulocyte Colony-Stimulating Factor, pharmacology, Humans, In Vitro Techniques, Integrin beta3, genetics, Male, Pregnancy, RNA, Messenger, genetics, Receptors, Urokinase Plasminogen Activator, genetics, Signal Transduction, drug effects, Thymidine Phosphorylase, genetics
Référence
PLoS One. 2014 10 2;9(9):e102286
